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It's often caused by a sexually transmitted infection (STI). No Differences in Outcome after Intracytoplasmic Sperm Injection with Fresh or with Frozen-thawed Epididymal Spermatozoa. (PDF, 66 KB) Human Reproduction, 1999.

Factors effecting normal expectancy of conception. Chemotherapy: Some chemotherapy drugs can result in ovarian failure. This process has revolutionized assisted reproductive technology and the way reproductive endocrinologists can help people in having a baby.

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There is more controversy regarding intramural fibroids, where larger ones may have an impact and may necessitate removal. Most typical are decreased libido, erectile dysfunction, orgasmic dysfunction, and ejaculatory dysfunction. The most common technique of artificial insemination in human beings is intrauterine insemination. Unexplained infertility in women or men may be managed with another year of unprotected intercourse, or may proceed to assisted reproductive technologies, such as intrauterine insemination or in vitro fertilization. However, it could be the future for the treatment of multiple diseases, including infertility. If conception does not occur after many months or years of trying, it can lead to stress and possibly depression.

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An Azoospermic Man with a do novo Point Mutation in the Y-chromosome Gene USP9Y. (PDF, 381 KB) Nature Genetics, 1999. The likelihood of fertilization improves significantly for men with low sperm concentrations. Causes in women Infertility in women can also have a range of causes.

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This similarity is sufficient to achieve binding by estrogen receptors, including the receptors of the hypothalamus. 8 These studies are more sensitive and may delineate an abnormally formed uterus or structural problems, such as fibroids. 3  Sometimes, a couple who’ve already had a child can have trouble conceiving again. Several days later, embryos -- or fertilized eggs -- get put back into your uterus with a device called an intrauterine insemination catheter. In such circumstances, it is recommended not to prescribe any medication until all basic investigations are done and its results received. Physical Problems A variety of physical problems can cause male infertility.  These problems either interfere with the sperm production process or disrupt the pathway down which sperm travel from the testes to the tip of the penis.  These problems are usually characterized by a low sperm count and/or abnormal sperm morphology.  The following is a list of the most common physical problems that cause male infertility: Variocoele: A varicocele is an enlargement of the internal spermatic veins that drain blood from the testicle to the abdomen (back to the heart) and are present in 15% of the general male population and 40% of infertile men.  These images show what a variocoele looks like externally and internally.  A varicocele develops when the one way valves in these spermatic veins are damaged causing an abnormal back flow of blood from the abdomen into the scrotum creating a hostile environment for sperm development.  Varicocoeles may cause reduced sperm count and abnormal sperm morphology which cause infertility.  Variococles can usually be diagnosed by a physical examination of the scrotum which can be aided by the Doppler stethoscope and scrotal ultrasound.  Varicocoele can be treated in many ways (see treatment section), but the most successful treatments involve corrective surgery. Female age of 35 years or older: For unclear reasons, egg numbers decrease at a rapid rate as women age. These abnormalities can also cause irregular bleeding between menstrual cycles. Y Chromosome Deletions in Azoospermic and Severely Oligozoospermic Men Undergoing Intracytoplasmic Sperm Injection after Testicular Sperm Extraction. (PDF, 336 KB) Human Reproduction, 1998. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. The diagnostic charts, which may be photocopied, provide an unambiguous route to diagnosis of the underlying cause of infertility, whilst the text fully explains and describes the essential clinical tests.