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World Health Organization[edit] The World Health Organization defines infertility as follows:[10] United States[edit] One definition of infertility that is frequently used in the United States by reproductive endocrinologists, doctors who specialize in infertility, to consider a couple eligible for treatment is: a woman under 35 has not conceived after 12 months of contraceptive-free intercourse. Sperm motility Motility is described as the percent of sperm present with flagellar motion viewed on a bright-field or phase-contrast microscope.

For a man to be fertile, the testicles must produce enough healthy sperm to be ejaculated effectively into the woman's vagina. ZIFT is often called “tubal embryo transfer.” As with IVF, the actual fertilization of the eggs is observed and confirmed in the laboratory. These numbers are comparable to those of other industrialized nations.

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Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. Many infertile couples have had some previous assessment for their infertility and this data should be cautiously reviewed. A specific portion of the androgen receptor gene, exon 1, has been studied in infertile males and a meta-analysis that involved males with idiopathic infertility and fertile controls found that infertility was directly correlated with the length of CAG repeats in this exon.[23] Y chromosome microdeletion syndrome The long arm of the Y chromosome (Yq) is considered critical for fertility, especially Yq11. The identification of anovulation is not easy; contrary to what is commonly believed, women undergoing anovulation still have (more or less) regular periods.

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Linthicum, Md.: American Urological Association, Inc.; 2010. A rapid slide agglutination test (RSAT) kit to detect serum antibodies is commercially available. Additionally, because insulin-like growth factor (IGF) has been shown to have an effect on semen quality, its role in varicocele pathology has been studied.[25] One study showed that IGF levels significantly increased after a varicocelectomy to levels that were no different than fertile controls, suggesting that varicocele-related infertility may involve IGF.[26] Varicoceles lead to an increased incidence of sperm immaturity, apoptosis, and necrosis with severe disturbances in meiotic segregation compared to fertile men without varicoceles, and these parameters generally improve after repair.

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What Forms of Male Infertility are there left to Cure? (PDF, 2 MB) Human Reproduction, 1995. The follicles are suctioned and microscopically examined afterward. It delivers a constant supply of Gn-RH to the pituitary gland, which alters the production of hormone, allowing the doctor to induce follicle growth with FSH. If a woman needs an HCG injection to activate ovulation and ultrasound scans show that too many follicles have developed, it is possible to withhold the HCG injection. Both infertility and subfertility are defined as the inability to conceive after a certain period of time (the length of which vary), so often the two terms overlap. S. women, or 6% of the married population 15 to 44 years of age, reported infertility, and 6. Basal body temperatures are no longer considered a reliable indicator of ovulation, and are not recommended for evaluating ovulation. These abnormalities can also cause irregular bleeding between menstrual cycles.