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For this reason, it is less likely to adversely affect the endometrium and cervical mucus. These microdeletions are not observed on regular karyotype testing; rather, their identification requires polymerase chain reaction (PCR)–based sequence-tagged site mapping or Southern blot analysis. 8,26,27 As opposed to laparoscopy or hysteroscopy, hysterosalpingography is a minimally invasive procedure with potentially therapeutic effects and should be considered before more invasive methods of assessing tubal patency.

About 25% of all infertility is caused by an ovulation disorder. 30–32 Other treatment options include antiestrogens and gonadotropin therapy, which showed a trend toward increased live birth rates in a Cochrane review. Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Reproductive Endocrinology and Infertility. A relationship also exists between obesity and erectile dysfunction (ED).

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Similarly, bilateral obstruction of the sperm ducts can cause azoospermia and infertility. As an antiestrogen, CC requires that the patient have some circulating estrogen levels; otherwise, the patient will not respond to the treatment. Without an erection, it is difficult for a man to release sperm inside the vagina—and, therefore, difficult to get a woman pregnant. 8  A normal sample according to the 2010 World Health Organization (WHO) guidelines is described in Table 2.

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Women with anovulation may be treated in the primary care setting with clomiphene to induce ovulation. Requirements for Female Fertility (Continued) Other requirements for female fertility include: Adequate sexual drive and sexual function to permit coitus. Recombination Between Palindromes P5 and P1 on the HUman Y Chromosome Causes Massive Deletions and Spermatogenic Failure. (PDF, 786 KB) The American Journal of Human Genetics, 2002. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service.

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A bicornuate uterus can be associated with a history of recurrent miscarriages, and its repair is indicated only if other etiologies for the miscarriage have been excluded (see Surgical intervention below). To assist in the luteal phase, the patient is given beta-HCG or progesterone. If he has two X chromosomes and one Y chromosome, as in Klinefelter's syndrome, the testicles will develop abnormally and there will be low testosterone and a low sperm count or no sperm. This may be used if IVF has not been effective, if there has been poor embryo growth rate, and if the woman is older. As the amount of adipose tissue increases, there is more aromatase available to convert androgens, and serum estradiol levels increase. It binds in a part of the brain called the hypothalamus, which is essential in stimulating the ovary to grow and release an egg. Ovary Transplantation for Fertility Preservation in Cancer Patients: Fresh and Frozen. (PDF, 1 MB) Chapter 42 from textbook Clinial Infertility, 2010. Chromosomal Abnormalities in Embryos Derived from Testicular Sperm Extraction. (PDF, 324 KB) Fertility and Sterility, 2003.