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Several methods are available to detect antisperm antibodies, such as radioimmunoassay and enzyme-linked immunosorbent assay, but the most specific test is the immunobead test. Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. When the eggs are mature, your doctor collects them with a device called a vaginal ultrasound probe. If a semen analysis is found to be abnormal, generally it is first repeated to confirm the abnormality.

However, hormones are not the main problem in 97% of infertile men. 7) Endometriosis: Endometriosis is a condition whereby cells very similar to the ones lining the uterine cavity, or endometrium, are found outside the uterine cavity.

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These drugs also can also help you get pregnant by causing your ovaries to release multiple eggs. 8,37 Women in WHO group II, including those who are overweight and who have polycystic ovary syndrome, can benefit from weight loss, exercise, and lifestyle modifications to restore ovulatory cycles and achieve pregnancy.

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Medications, treatments, and drugs Some drugs can affect fertility in a woman. Treatment of Female Infertility: Intrauterine Insemination Intrauterine insemination (IUI) is a fertility procedure in which sperm are washed (separated from the semen), concentrated, and injected directly into a woman’s uterus. The impact of small or single polyps is more controversial. Earn up to 6 CME credits per issue.     To see the full article, log in or purchase access. The enzyme aromatase is responsible for this conversion, and is found primarily in adipose tissue. Additional risk factors may include smoking, alcohol use, obesity, and older age; however, the data are hampered by a lack of pregnancy-related outcomes.

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Female factor infertility is typically to blame 40 percent of the time, while male factor infertility is the cause of issues 30 to 40 percent of the time. Leptin is a hormone associated with numerous effects including appetite control, inflammation, and decreased insulin secretion, according to many studies. Reifenstein syndrome in males involves partial androgen insensitivity in males and presents as a spectrum of abnormal external genitalia and infertility.[22] Because cells inadequately respond to androgen stimulation, spermatogenesis is impaired. Varicocele: Surgically removing a varicose vein in the scrotum may help. Low weight: Obesity is not the only way in which weight can impact fertility. Anabolic steroids: Popular with bodybuilders and athletes, long-term use can seriously reduce sperm count and mobility. Abundant Gene Conversion Between Arms of Palindromes in Human and Ape Y Chromosomes. (PDF, 340 KB)Nature, 2003. Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women. Therefore, pelvic ultrasonography is required before CC is initiated. [207] Pure FSH treatment for ovulation induction is another alternative for patients with PCOS who are clomiphene resistant. Hysterosalpingogram (HSG) – This test is essential for evaluating fallopian tubal patency, uterine filling defects such as fibroids and polyps, and scarring of the uterine cavity (Asherman syndrome). Causes in men The following are common causes of infertility in men. It varies with the age (the optimal female age is between 23 and 39 years) and with body weight (the ideal body mass index is between 19 and 30). Evaluation may be initiated sooner in patients who have risk factors for infertility or if the female partner is older than 35 years.