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Hyperprolactinemia: If prolactin levels are high, and the woman is not pregnant or breastfeeding, it may affect ovulation and fertility. Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Reproductive Endocrinology and Infertility. If the sperm do not have the right shape, or they cannot travel rapidly and accurately towards the egg, conception may be difficult. The sperm must provide the zygote with DNA, centrioles, and activation factor for the embryo to develop. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997.

In-vitro fertilization and donor insemination are major procedures involved. In the testicle, germ cells (especially up to the preleptotene stage) are especially at risk. Bromocriptine is used in cases when anovulation is caused by an elevated level of the hormone prolactin. The enzyme aromatase is responsible for this conversion, and is found primarily in adipose tissue.

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It is often defined as not conceiving after 12 months of regular sexual intercourse without the use of birth control. Ovulation disorders can be treated with ovulation-inducing drugs. Due to the relative high cost of the equipment required, however, it has not become commonplace in most traditional practices today but rather limited to specialty-type practices.

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The agents most often associated with infertility are the alkylating agents such as cyclophosphamide. Options include intrauterine insemination (also known as IUI) or IVF with intracytoplasmic sperm injection (also known as ICSI).

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An Azoospermic Man with a do novo Point Mutation in the Y-chromosome Gene USP9Y. (PDF, 381 KB) Nature Genetics, 1999. Spermatogonia rest on the basement membrane and contain dense nuclei and prominent nucleoli. Exposure to toxic agents can occur from occupational hazards or contaminated air, water, food supply or other exposures. Men should also avoid hot baths and whirlpools, he says, because the high temperatures slow down your sperm factory. Sexually transmitted infections (STIs): Chlamydia can damage the fallopian tubes in a woman and cause inflammation in a man's scrotum. Consequently, amenorrhea, an anovulatory cycle, and corpus luteum deficiency can develop. A Physical Map of the Human Y Chromosome. (PDF, 160 KB) Nature, 2001. Undescended testicle may be isolated or may be observed as part of a syndrome such as prune belly syndrome. Sperm are nourished by semen, which is made by glands along the way. The fertilized egg attaches itself to the uterus (implantation) and begins to grow.  Predict your cycle with Flo! Females[edit] The following causes of infertility may only be found in females. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). A dye test may be performed to detect any blockage in the reproductive tract, wherein a dark blue dye is passed up through the cervix and is followed with the laparoscope through its passage out into the fallopian tubes to the ovaries.[1] See also[edit] [edit] External links[edit] Feder, Barnaby J.Infertility is the inability of a person, animal or plant to reproduce by natural means.