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Sexually transmitted infections (STIs): Chlamydia can damage the fallopian tubes in a woman and cause inflammation in a man's scrotum. Epididymal and Testicular Spermatozoa and Intracytoplasmic Sperm Injection. (PDF, 7 MB) Assisted Reproduction Reviews, 1996.

Obtaining morning levels of total testosterone (normal range = 240 to 950 ng per dL [8. Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women. Clinical diagnostic testing for the cytogenetic and molecular causes of male infertility: the Mayo Clinic experience. Histologic endometrial dating is not considered reliable nor is it predictive of fertility. Causes Potential causes of male infertility are: The complete absence of sperm (azoospermia) Low sperm count (oligospermia) Abnormal sperm shape (teratozoospermia) Problems with sperm movement (asthenozoospermia) Sperm that is completely immobile (necrozoospermia); the sperm may be alive and not moving, or they may be dead Problems with sperm delivery, due to sexual dysfunction, an obstruction, previous vasectomy, or retrograde ejaculation Problems with erections or other sexual problems There are a variety of conditions that may lead to male infertility. United Kingdom[edit] In the UK, previous NICE guidelines defined infertility as failure to conceive after regular unprotected sexual intercourse for two years in the absence of known reproductive pathology.[11] Updated NICE guidelines do not include a specific definition, but recommend that "A woman of reproductive age who has not conceived after 1 year of unprotected vaginal sexual intercourse, in the absence of any known cause of infertility, should be offered further clinical assessment and investigation along with her partner, with earlier referral to a specialist if the woman is over 36 years of age."[12] Other definitions[edit] Researchers commonly base demographic studies on infertility prevalence on a five-year period.[13] Practical measurement problems, however, exist for any definition, because it is difficult to measure continuous exposure to the risk of pregnancy over a period of years.

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Hypothalamic-pituitary-gonadal axis stimulatory and inhibitory signals. 6,28 Additionally, postcoital testing of cervical mucus is no longer recommended because it does not affect clinical management or predict the inability to conceive. Empirical treatment with controlled ovarian hyperstimulation followed by intrauterine insemination has improved the pregnancy rate in those patients. [214] If pregnancy does not occur during the first 4 intrauterine insemination cycles, other alternatives include IVF or any of the associated assisted reproductive technologies procedures.Background Infertility is a common clinical problem. Medicines and drugs Certain types of medicines can sometimes cause infertility problems. What’s on the Mind of IVF Consumers? (PDF, 627 KB) Reproductive BioMedicine Online, 2009.

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Vasectomy and its Microsurgical Reversal. (PDF, 17 MB) Urologic Clinics of North America, 1978. There are four parameters analyzed: 1) semen volume – should be at least 1.

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Intracytoplasmic Sperm Injection. (PDF, 4 MB) Chapter 47 from textbook Current Therapy in Equine Reproduction, 2006. Microsurgical Solutions to Male Infertility. (PDF, 2 MB) Contemporary OB/GYN, 2005. Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. A combination of all of these conditions is accordingly termed oligoasthenoteratozoospermia or short OAT syndrome. Overweight or obesity: This may reduce the chance of conceiving. Causes in men The following are common causes of infertility in men. Ovarian dysfunction, when a woman’s ovaries are not producing eggs, or egg production has diminished due to hormonal imbalance, age or other factors. Letrozole has a very short half-life (45 hours) and, therefore, is quickly cleared from the body. Most couples (about 84%) who have regular sexual intercourse (that is, every two to three days) and who do not use contraception get pregnant within a year. Varicoceles are generally asymptomatic, and most men with varicoceles do not have infertility or testicular atrophy. Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Primary infertility is when a couple has not conceived after trying for at least 12 months without using birth control Secondary infertility is when they have previously conceived but are no longer able to. Computer-aided semen analysis (CASA) Introduced in the late 1980s, CASA uses a video camera and computer to visualize and analyze sperm concentration and movement.