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Adverse effects of metformin include GI intolerance, nausea, vomiting, and abdominal cramps. One of the best known is the HFEA – The UK's regulator for fertility treatment and embryo research. Earn up to 6 CME credits per issue.     To see the full article, log in or purchase access. Hjollund NH, Storgaard L, Ernst E, Bonde JP, Olsen J.

Overweight or obesity: This may reduce the chance of conceiving. Some medications increase the risk of fertility problems in men. Testosterone is a key hormone for male fertility, so problems with the testes that produce this hormone may lead to infertility. In this case, your doctor may recommend advanced fertility treatment — assisted reproductive technologies (ART) treatment. Intracytoplasmic Sperm Injection Today: A Personal Review. (PDF, 5 MB) Human Reproduction, 1998.

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The vas deferens carries sperm from the epididymis to the ejaculatory duct and the urethra. Eating disorders such as anorexia nervosa are also associated with extremely low BMI. It can also help if a man has severe erectile dysfunction.

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6,8 It is important for primary care physicians to be familiar with the workup and prognosis for infertile couples. The secondary spermatocytes undergo a second meiosis and become spermatids. According to the literature survey, the most common causes of infertility are: male factor [5,7-9,13-15] such as sperm abnormalities [9,13,15], female factor [7-9,14-16] such as ovulation dysfunction [7,8] and tubal pathology [7-9], combined male and female factors [7,9,14,15] and unexplained infertility; where no obvious cause could be detected [7-9]. Alternatively, the patient may bypass surgical treatment and proceed directly to intrauterine insemination or in vitro fertilization, depending on the severity and the female partner's age. Investigations will be requested to prove the clinical diagnosis and to exclude other close possibilities.

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Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. Male and female factors can exist in isolation or combination and fertility investigations, diagnoses and treatment should always be considered in the context of the couple.       Male factor Sperm problems will contribute to about 40% of infertility cases. It may come as a surprise if you’ve spent most of your adult life trying to avoid it, but conceiving is actually a lot harder than you may expect. Efficacy of laparoscopy is inferior to open surgery in certain conditions such as pyloromyotomy for Infantile hypertrophic pyloric stenosis. Search dates: January 6, 2014; January 28, 2014; February 5, 2014; and November 18, 2014. Other causes of ovulation disorders include ovarian insufficiency and hypothalamic amenorrhea. If a person is experiencing other symptoms, they may wish to speak to a doctor. National Collaborating Centre for Women's and Children's Health.