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Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Women in group III can conceive only with oocyte donation and in vitro fertilization. Thus one of the requirements is normal spermatogenesis – normal sperm count, motility and biologic structure and function.

Chromosomal Abnormalities in Embryos Derived from Testicular Sperm Extraction. (PDF, 324 KB) Fertility and Sterility, 2003. Human menopausal gonadotropin, or hMG (Repronex): This contains both FSH and LH. Clomiphene citrate and/or Metformin. - folliculometry via TVUSS should be done to avoid multiple pregnancies and risk of OHSS. - Not for more than 6 months. Do you have a family history of medical problems? The Avon Longitudinal Study of Pregnancy and Childhood Study Team. Judaism and Repoductive Technology. (PDF, 160 KB) 2003.

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Vasectomy and Vasectomy Reversal. (PDF, 7 MB) Fertility and Sterility, 1978. 38,39 Family physicians may choose to attempt ovulation induction in anovulatory women (WHO group II) with clomiphene.

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The initial dosage of clomiphene is 50 mg daily for five days starting on day 3 to 5 of the menstrual cycle. Moderate ovarian hyperstimulation syndrome is characterized by ovarian enlargement (5-12 cm in diameter) moderate ascites, nausea, vomiting, abdominal discomfort, and weight gain greater than 10 lb. Malformations are the primary organic causes of sterility. New Concepts in Operative Andrology: A Review. (PDF, 7 MB) International Journal of Andrology, 2000.

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Prozac and other SSRIs, Propecia).  Luckily, many treatment options exist for ED depending on the cause--these will be discussed in the treatment section. Outside pregnancy and lactation, women with high levels of prolactin may have irregular ovulation cycles and fertility problems. Congenital Absence of the Vas Deferens: The Fertilizing Capacity of Human Epididymal Sperm. (PDF, 3 MB) New England Journal of Medicine, 1990. Coping mentally It is impossible to know how long treatment will go on for and how successful it will be. Men can still ejaculate with a low sperm count or poor-quality sperm. Follicle-stimulating hormone (Gonal-F, Bravelle): This hormone is produced by the pituitary gland that controls estrogen production by the ovaries. Thankfully, even when the cause of infertility is not known, various fertility treatments can overcome the unknown road block that was preventing pregnancy and eventually lead to delivery of a healthy baby. Duration of Fertility after Fresh and Frozen Ovary Transplantation. (PDF, 606 KB) Fertility and Sterility, 2010. In patients with low gonadotropins and low estrogen, the treatment of choice is hMG, and the protocol is similar to that for patients with primary amenorrhea. Primary spermatocytes undergo meiosis as the cells successively pass through the preleptotene, leptotene, zygotene, and pachytene stages to become secondary spermatocytes. To Transplant or Not to Transplant – That Is the Question. (PDF, 3 MB) 2010. Sperm Granuloma and Reversibility of Vasectomy. (PDF, 11 MB) Lancet, 1977.