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Intrauterine insemination 50% of women will conceive after 6 cycles. Half of the unsuccessful ones, will conceive with further 6 cycles. It is artificial introduction of semen inside the female’s uterus. Success rate varies, lie between 15% to 20% per cycle. Poor egg quality: Eggs that are damaged or develop genetic abnormalities cannot sustain a pregnancy. Nonchromosomal testicular failure Testicular failure that is nonchromosomal in origin may be idiopathic or acquired by gonadotoxic drugs, radiation, orchitis, trauma, or torsion.

Twelve months is the lower reference limit for Time to Pregnancy (TTP) by the World Health Organization.[7] a woman over 35 has not conceived after six months of contraceptive-free sexual intercourse. When the big veins heat the testes too much, the heat damages the sperm. Females[edit] The following causes of infertility may only be found in females. Testosterone is secreted in a diurnal pattern, peaking a few hours after the man awakens from sleep. Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Although many of these can be treated through surgery or hormonal substitutions, some may be indefinite.[59] Infertility associated with viable, but immotile sperm may be caused by primary ciliary dyskinesia.

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If the tubes are blocked, the sperm cannot travel into and out of the penis making it impossible for the sperm to ever meet with and fertilize an egg. Source : Medications Used With Infertility Treatment PPT Presentation Summary : Medications Used with Infertility Treatment. Patients with azoospermia or severe oligospermia seeking assisted reproductive techniques should be screened. KU School of Medicine Source : Are Twins An Adverse Outcome After Infertility Treatments? Investigations Infertile couples are usually adviced to start their investigations after 12 months of trying to conceive or after 6 months if the female partner is more than 35 years old or immediately if there is an obvious cause for their infertility or subfertility [16].

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The Treatment of Azoospermia with Surgery and ICSI. (PDF, 4 MB) Chapter 10 from Male Fertility & Infertility, 1998. Egg donation. This can help you if you have ovaries that don't work right but you have a normal uterus.

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Factors effecting normal expectancy of conception. It is specially oriented for cancer patients, whose sperm is destroyed due to the gonadotoxic treatment they are submitted to.[70] Ovaric stem cells: it is thought that women have a finite number of follicles from the very beginning. Pregnancy After Testicular Transplant: Importance of Treating the Couple. (PDF, 5 MB) Fertility and Sterility, 1980. When one year of sexual relationships without birth control measures has not lead to a pregnancy. Male and female factors can exist in isolation or combination and fertility investigations, diagnoses and treatment should always be considered in the context of the couple.       Male factor Sperm problems will contribute to about 40% of infertility cases. Age plays quite a critical role, as fertility peaks for both men and women in their mid-twenties. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. The rising number of obese individuals may be due in part to an energy-rich diet as well as insufficient physical exercise.  In addition to other potential health risks, obesity can have a significant impact on male and female fertility. This may be used if IVF has not been effective, if there has been poor embryo growth rate, and if the woman is older. A woman of reproductive age who is using artificial insemination to conceive (with either partner or donor sperm) after 6 failed trials. Consider earlier referral to infertility specialists where: - the woman is aged 36 years or over. - there is a known clinical cause of infertility or a history of predisposing factors for infertility. - treatment is planned that may result in infertility (such as treatment for cancer). - People who are concerned about their fertility and who are known to have chronic viral infections such as hepatitis B, hepatitis C or HIV. In such cases, OPKs and those fertility monitors which are based on LH may show false results, with an increased number of false positives or false negatives.