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A bicornuate uterus can be associated with a history of recurrent miscarriages, and its repair is indicated only if other etiologies for the miscarriage have been excluded (see Surgical intervention below). Infertility: Female and Male Factors It is very important to note that infertility can occur as a result of one or more male or female factors. A couple which is unable to conceive is not the same as a couple which often conceives without difficulties but which then sadly finds that the pregnancy does not go full term.

Absence of the main sperm pipeline known as the vas deferens. Additional risk factors may include smoking, alcohol use, obesity, and older age; however, the data are hampered by a lack of pregnancy-related outcomes. Associated conditions[edit] For most women, alteration of menstrual periods is the principal indication of chronic anovulation. Illegal drugs: Some women who use marijuana or cocaine may have fertility problems.

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It is increasingly recognized that egg quality is of critical importance and women of advanced maternal age have eggs of reduced capacity for normal and successful fertilization. After ruling out female infertility concerns, tests for male infertility may be needed.

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Eating disorders such as anorexia nervosa are also associated with extremely low BMI. In many instances, sterility may be unexplained, but fertility treatments will be able to help. Y Chromosome Deletions in Azoospermic and Severely Oligozoospermic Men Undergoing Intracytoplasmic Sperm Injection after Testicular Sperm Extraction. (PDF, 336 KB) Human Reproduction, 1998. A Modern View of Male Infertility. (PDF, 7 MB) From The Infertile Male: Advanced Assisted Reproductive Technology, 1994.

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Advances in assisted reproductive technologies, such as IVF, can offer hope to many couples where treatment is available, although barriers exist in terms of medical coverage and affordability. The agents most often associated with infertility are the alkylating agents such as cyclophosphamide. Bensdorp AJ, Cohlen BJ, Heineman MJ, Vandekerckhove P. A relationship also exists between obesity and erectile dysfunction (ED). If oligospermia or azoospermia is noted, hypogonadism should be suspected. Semen that is not initially a coagulum is often an indication of an ejaculatory duct obstruction or the absence of seminal vesicles. However, a complete blockage of the ovaries is rarely a cause of infertility. Obesity and increased risk for oligozoospermia and azoospermia. The Treatment of Azoospermia with Surgery and ICSI. (PDF, 4 MB) Chapter 10 from Male Fertility & Infertility, 1998. These include: non-steroidal anti-inflammatory drugs (NSAIDs) – long-term use or a high dosage of NSAIDs, such as ibuprofen or aspirin, can make it more difficult to conceive chemotherapy – medicines used for chemotherapy can sometimes cause ovarian failure, which means your ovaries will no longer be able to function properly neuroleptic medicines – antipsychotic medicines often used to treat psychosis; they can sometimes cause missed periods or infertility spironolactone – a type of medicine used to treat fluid retention (oedema); fertility should recover around 2 months after you stop taking spironolactone Illegal drugs, such as marijuana and cocaine, can seriously affect fertility and make ovulation more difficult. Vasectomy Reversal. (PDF, 733 KB) The New England Journal of Medicine, 1977. 8 Couples with unexplained infertility may want to consider another year of intercourse before moving to more costly and invasive therapies, such as assisted reproductive technology.