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Factors affecting Fertility Low body weight - Women with BMI less than 19 and irregular menstruation should be counselled to gain weight. Smoking - Strong association between smoking and fertility in both partners. - Affects success rates of ARTs. Generally, evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse. Full history taking of both partners usually denotes the underlying problem [17-23], (Appendix 1). Estrogen excess may be seen in patients with Sertoli cell tumors, Leydig tumors, liver failure, or severe obesity. Testosterone is a key hormone for male fertility, so problems with the testes that produce this hormone may lead to infertility.

Mannitol Induced Central Nervous System Toxicity in Renal Failure. (PDF, 4 MB) Investigative Urology, 1972. Worldwide, 8 to 12 percent of couples experience fertility problems. Treatment of Tubal and Peritoneal Factors The treatment of tubal-factor infertility underwent major changes, especially during the last quarter of the century when microsurgery became available. [126, 127] Tubal reconstruction was the only hope for those patients before assisted reproductive therapy became available.

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Fertilization takes place outside the body, and the fertilized egg is reinserted into the woman's reproductive tract, in a procedure called embryo transfer. High-cost treatments are out of financial reach for some couples.

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Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. There is no reliable means to predict whether the use of any treatment option will be successful and after how many attempts. Assessment of efficacy of varicocele repair for male subfertility: a systematic review. During this time, the cells cross from the basal to the adluminal compartments. Functional sperm that are present may have a normal karyotype. The success of the procedure is related to the diameter of the hydrosalpinx and to the damage to the cilial epithelium.

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Although many of these can be treated through surgery or hormonal substitutions, some may be indefinite.[59] Infertility associated with viable, but immotile sperm may be caused by primary ciliary dyskinesia. Infertility tests for women A woman will undergo a general physical examination, and the doctor will ask about her medical history, medications, menstruation cycle, and sexual habits. Transitions of the tube mucosa with luminal adhesions develop from recent infections of the genitalia involving the adnexa. Luciano AA, Peluso J, Koch EI, Maier D, Kuslis S, Davison E. Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis.(PDF, 958 KB) Reproductive BioMedicine Online, 2010. However, there are side effects to using fertility drugs, such as ovarian hyperstimulation or the increased chance of developing ovarian tumors.  Surgical procedures: These surgeries correct abnormalities or blockages in the uterus and fallopian tubes. Surgical procedures for women If the fallopian tubes are blocked or scarred, surgical repair may make it easier for eggs to pass through.