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Causes Potential causes of male infertility are: The complete absence of sperm (azoospermia) Low sperm count (oligospermia) Abnormal sperm shape (teratozoospermia) Problems with sperm movement (asthenozoospermia) Sperm that is completely immobile (necrozoospermia); the sperm may be alive and not moving, or they may be dead Problems with sperm delivery, due to sexual dysfunction, an obstruction, previous vasectomy, or retrograde ejaculation Problems with erections or other sexual problems There are a variety of conditions that may lead to male infertility. The chromosomal pattern of the resultant embryos can be assessed with preimplantation genetic diagnosis. Other conditions Various other lesions and diseases, such as CNS tumors, temporal lobe seizures, and many drugs (eg, dopamine antagonists) may interrupt the hypothalamic-pituitary axis at the hypothalamus. The medicalization of infertility has unwittingly led to a disregard for the emotional responses that couples experience, which include distress, loss of control, stigmatization, and a disruption in the developmental trajectory of adulthood.[16] Infertility may have psychological effects.

10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. Ectopic pregnancy This is when a fertilized egg implants outside the womb, usually in a fallopian tube. Cushing disease Increased cortisol levels cause a negative feedback on the hypothalamus, decreasing GnRH release. Testis Biopsy and the Infertile Male. (PDF, 20 MB) Chapter 15 from textbook Office Andrology, 2005.

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View Media Gallery Seminiferous tubules are made up of Sertoli cells and germ cells and are surrounded by peritubular and myoid cells. Treatment of Hemorrhage from Renal Trauma by Angiographic Injection of Clot. (PDF, 1 MB) The Journal of Urology, 1978. Regardless of the treatment approach, establish a 6- to 12-month interval during which a spontaneous pregnancy is expected to occur. Medicines and drugs  The side effects of some types of medicines and drugs can affect your fertility. In some cases, the egg may have matured properly, but the follicle may have failed to burst (or the follicle may have burst without releasing the egg). What Forms of Male Infertility are there left to Cure? (PDF, 2 MB) Human Reproduction, 1995.

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Regression of Metastases after Nephrectomy for Renal Cell Carcinoma. (PDF, 1 MB) British Journal of Urology, 1975. This is obviously extremely distressing for the couples involved. The Relationship of Abnormal Semen Parameters to Male Fertility. (PDF, 4 MB) Human Reproduction, 1989. Limits were placed on language and human race as well. Semen is the milky fluid that a man's penis releases during orgasm.

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Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994. You take gonadotropins that trigger the development of more than one egg. The chance of a multiple birth is lower with an oral fertility drug. A man’s age significantly affects coital frequency and sexual function. Delayed conception and active and passive smoking. Treatment of the cause: 27. Tubal and uterine factors: 1. Outlook For couples who experience fertility problems and those who wish to have children at an older age, there are more options available than ever before. Role of Epididymis in Sperm Maturation. (PDF, 3 MB) Urology, 1989. Fertility treatment with donor eggs is usually done using IVF. One type of ovulation problem, polycystic ovarian syndrome, is effectively treated with medications. Some people find that joining a support group helps, as it offers the chance to talk to others in a similar situation. Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis.(PDF, 958 KB) Reproductive BioMedicine Online, 2010. Female and male factors are equally responsible for infertility. Thus one of the requirements is normal spermatogenesis – normal sperm count, motility and biologic structure and function.