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Ovarian Transplantation between Monozygotic Twins Discordant for Premature Ovarian Failure. (PDF, 315 KB) The New England Journal of Medicine, 2005. Suspect antisperm antibodies when semen analysis reveals abnormal clumping, agglutination, unexplained decreased motility, or an abnormal postcoital test result. Hypothalamic-pituitary-gonadal axis stimulatory and inhibitory signals. Ovarian Transplantation between Monozygotic Twins Discordant for Premature Ovarian Failure. (PDF, 315 KB) The New England Journal of Medicine, 2005.

Semen and sperm Sometimes the sperm cannot travel effectively to meet the egg. The presence of anti-sperm antibodies have been found in infertile men, and suppression of these antibodies with corticosteroid treatment has improved the semen quality and increased the rate of conception. Testicular neoplasia, commonly producing estrogen, usually causes infertility. Gynecological history, including operations and medical treatment. Outcome of Intracytoplasmic Sperm Injection with Testicular Spermatozoa in Obstructive and Non-obstructive Azoospermia. (PDF, 426 KB) Human Reproduction, 1996. ART techniques generally start with stimulating the ovaries to increase egg production.

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Primary infertility is when a couple has not conceived after trying for at least 12 months without using birth control Secondary infertility is when they have previously conceived but are no longer able to. Submucosal fibroids: Benign or non-cancerous tumors occur in the muscular wall of the uterus.

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As treatment begins, couples may experience cycles of optimism and despair with each passing menstrual cycle. Role of Semen Analysis in Subfertile Couples. (PDF, 250 KB) Fertility and Sterility, 2010.

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Thankfully, even when the cause of infertility is not known, various fertility treatments can eventually lead to delivery of a healthy baby. This can reveal signs of endometriosis, scarring, blockages, and some irregularities of the uterus and fallopian tubes. It is often defined as not conceiving after 12 months of regular sexual intercourse without the use of birth control. Vasectomy and Vasectomy Reversal. (PDF, 7 MB) Fertility and Sterility, 1978. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. In these cases the duration of the infertility is the best parameter by which to judge the chances of future natural conception; the longer the time of infertility then the sooner intervention should be considered.April 23–29 is National Infertility Awareness Week and is intended to increase awareness of infertility, which affects the reproductive systems of both women and men (1). Erectile dysfunction, vaginismus (painful involuntary spasm of vagina preventing intercourse) and dyspareunia (pain during sexual intercourse) can explain involuntary childlessness in some couples.