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Antibodies that are bound to sperm decrease the sperm’s ability to penetrate the cervical mucus and bind to the zona pellucida. The Prevention of Acute Tubular Necrosis in Renal Transplantation by Chronic Salt Loading of the Recipient. (PDF, 627 KB) ANZ Journal of Surgery, 1974. 6 mg SC q4wk for 6 months) GnRHa therapy can be administered along with cyclic or continuous progestins or with cyclic or continuous estrogen and progestins in cases of severe hot flashes. [145, 152] Combined therapy Medical and surgical treatments are usually combined for the treatment of severe endometriosis. Once a follicle containing an egg reaches a mature size, another hormone injection called HCG is often given to mimic the natural LH surge that occurs at the time of ovulation.

These include: Infrequent menstrual periods: When a woman has regular menstrual periods, defined as regular cycles occurring every 21 to 35 days, this almost always indicates that she ovulates regularly. It is possible that this mechanism evolved to protect the mother’s health. Computer-aided semen analysis (CASA) Introduced in the late 1980s, CASA uses a video camera and computer to visualize and analyze sperm concentration and movement. For example, polycystic ovarian syndrome is when the eggs only partially developed within the ovary and there is an excess of male hormones.

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Assisted hatching: The embryologist opens a small hole in the outer membrane of the embryo, known as the zona pellucid. Congenital Adrenal Hyperplasia: Occurs when the pituitary is suppressed by increased levels of adrenal androgens.  Symptoms include low sperm count, an increased number of immature sperm cells, and low sperm cell motility.  Is treated with cortisone replacement therapy.  This condition is found in only 1 percent of infertile men.

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If an endocrinopathy, such as hyperprolactinemia, is diagnosed, the underlying cause should be treated. The problem is getting the sperm where they need to go. Abnormal sperm: The sperm may have an unusual shape, making it harder to move and fertilize an egg. Simultaneous Treatment of the Wife in Infertile Couples with Oligospermia. (PDF, 4 MB) Fertility and Sterility, 1983. Lifetime prevalence of infertility and infertility treatment in the UK: results from a population-based survey of reproduction.

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Illegal drugs: Some women who use marijuana or cocaine may have fertility problems. Testosterone and estradiol function as feedback inhibitors of gonadotropin release. Obstructions in the sperm transport plumbing can sometimes be surgically corrected. It is also important to increase the frequency of intercourse by having well-timed sex regularly to improve fertility. The use of surgical humidification therapy, which is the use of heated and humidified CO2 for insufflation, has been shown to reduce this risk.[27] Many patients with existing pulmonary disorders may not tolerate pneumoperitoneum (gas in the abdominal cavity), resulting in a need for conversion to open surgery after the initial attempt at laparoscopic approach. Recombination Between Palindromes P5 and P1 on the HUman Y Chromosome Causes Massive Deletions and Spermatogenic Failure. (PDF, 786 KB) The American Journal of Human Genetics, 2002.


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Infertility Research Project
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