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According to the literature survey, the most common causes of infertility are: male factor [5,7-9,13-15] such as sperm abnormalities [9,13,15], female factor [7-9,14-16] such as ovulation dysfunction [7,8] and tubal pathology [7-9], combined male and female factors [7,9,14,15] and unexplained infertility; where no obvious cause could be detected [7-9]. Less than 50% motility may significantly affect the ability for sperm to fertilize the egg without therapy; and (4) morphology, or shape – there are three parts of the sperm that are analyzed for morphology: the head, midpeice, and tail.

Results of one study investigating a cohort of 315 men revealed changes within the hinge region of SF-1 and no rare allelic variants in fertile control men. Chromosomal defects Hereditary disorders, such as Klinefelter’s syndrome (when a male is born with two X chromosomes and one Y chromosome instead of one X and one Y) impacts the normal development of the male reproductive organs. Up to 25% of infertile men have idiopathic infertility. Management of the infertile couple: an evidence-based protocol.

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What’s on the Mind of IVF Consumers? (PDF, 627 KB) Reproductive BioMedicine Online, 2009. Laparotomy is indicated in patients with severe pelvic adhesions that compromise the bowel, ovaries, and tubes, with obliteration of the cul-de-sac. [129] The aim of the procedure is to correct what is necessary to allow the normal transport of the gametes; complete restoration of the anatomy is not intended. [130] Lysis of adhesions should be meticulous, using hydrodissection and fine instruments.

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Search dates: January 6, 2014; January 28, 2014; February 5, 2014; and November 18, 2014. Treatment of hydrosalpinx (distal tubal obstruction) with salpingostomy can be performed through microsurgery or operative laparoscopy.

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Drawbacks of ICSI include unknown risks to the egg or embryo and damage to the embryo. Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens. (PDF, 5 MB) New England Journal of Medicine, 1995. Damaged Sperm Ducts: Seven percent of infertile men cannot transport sperm from their testicles to out of their penis.  This pathway may be blocked by a number of conditions: · A genetic or developmental mistake may block or cause the absence of one or both tubes (which   transport the sperm from the testes to the penis). · Scarring from tuberculosis or some STDs may block the epididymis or tubes. · An elective or accidental vasectomy may interrupt tube continuity. ARTICLES FROM THE 1990s Microsurgery, Andrology, and Its Role in IVF. (PDF, 6 MB) Chapter in text book, Advances in Assisted Reproductive Technology, 1990. Especially in men, psychological explanations should be considered as they are frequently the cause of sexual dysfunctions. If the epididymis is blocked, sperm may not be ejaculated properly. Endometrial biopsy should be performed only in women with suspected pathology (chronic endometritis or neoplasia). Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis.