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The most commonly prescribed pill to stimulate ovulation (generally of one mature egg) is clomiphene citrate. BMI (body mass index) may be a significant factor in fertility, as an increase in BMI in the male by as little as three units can be associated with infertility.

This results in negative feedback stimulation of the hypothalamic-pituitary axis, causing an increase release of gonadotropins and testosterone. The production of anti-sperm antibodies by the woman’s immune system can interfere with fertilization. Fluctuations in hormone levels can cause: unexplained weight gain severe acne cold feet and hands reduced sex drive or loss of sexual desire nipple discharge facial hair in females thinning hair on the top of the head Underlying medical conditions Other contributing factors that may affect fertility in women include: damage to the fallopian tubes or ovaries premature menopause PCOS endometriosis cancer and cancer treatments Obesity A 2018 study found that obesity might negatively affect reproductive health.

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ICSI offers a high pregnancy rate and 70—80 % of eggs are fertilized through this technique. These specimens benefit most from layering a washed pellet of sperm with nutrient media and allowing the motile fraction to swim up into the media before being separated. [109] After sperm preparation, the spermatozoa are enhanced in motility and become activated and ready to fertilize an oocyte.

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Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). Analyses of the CFTR Gene in 67 Patients. (PDF, 4 MB) The American Journal of Human Genetics, 1995.

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However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. 549 KB Effect of Age on Male Fertility. (PDF, 5 MB) Chapter from textbook, Seminars in Reproductive Endocrinology, 1991. Ejaculation disorders Ejaculation disorders include premature ejaculation, anejaculation (the failure to ejaculate), and retrograde ejaculation, which is when semen enters the bladder during orgasm instead of coming out the tip of the penis. For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. 8 Women in group I typically present with amenorrhea and low gonadotropin levels, most commonly from low body weight or excessive exercise. This can be related to hormone issues, or to polycystic ovarian syndrome (PCOS). Microscopic Vasoepididymostomy: Specific Microanastomosis to the Epididymal Tubule. (PDF, 15 MB) Fertility and Sterility, 1978. Ovulation often can be detected by keeping a menstrual calendar or using an ovulation predictor kit. If this is unsuccessful, the decision which form of artificial insemination is going to be used is made individually.