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Genital duct obstruction is a potentially curable cause of infertility and is observed in 7% of infertile patients. Successful Pregnancy and Delivery after Calcium Ionophore Oocyte Activation in a Normozoospermic Patient with Previous Failed Fertilization after Intracytoplasmic Sperm Injection. (PDF, 57 KB) Fertility and Sterility, 2003. Normal Intrauterine Pregnancy After Reversal of Tubal Sterilization in the Wife and Vasectomy in the Husband.(PDF, 1 MB) Fertility and Sterility, 1978.

Surgical Management of Male Infertility. (PDF, 2 MB) Chapter 12 from textbook, Male Infertility, 1992. Demographic definitions of infertility An inability of those of reproductive age (15-49 years) to become or remain pregnant within five years of exposure to pregnancy. (DHS2) An inability to become pregnant with a live birth, within five years of exposure based upon a consistent union status, lack of contraceptive use, non-lactating and maintaining a desire for a child. (Trends in prevalence4). Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004.

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The Three-kidney Rat Model. (PDF, 2 MB) Investigative Urology, 1974. As the amount of adipose tissue increases, there is more aromatase available to convert androgens, and serum estradiol levels increase. Temporal relationship and reliability of the clinical, hormonal, and ultrasonographic indices of ovulation in infertile women. The majority of men with varicocele present no symptoms. Health problems such as mumps or hormone problems. 37 Clomiphene has also proven effective for ovulation induction in women with polycystic ovary syndrome.

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3) Insemination: Intrauterine insemination, also known as IUI, is a process by which sperm is washed and prepared for placement into the uterine cavity, therefore bypassing the cervix and bringing a higher concentration of motile sperm closer to the tubes and ovulated egg. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. Previously, metformin was recommended as treatment for anovulation in polycystic ovary syndrome, but in the largest trial to date, comparing clomiphene with metformin, clomiphene was more effective than metformin alone.[21] Following this study, the ESHRE/ASRM-sponsored Consensus workshop do not recommend metformin for ovulation stimulation.[22] Subsequent randomized studies have confirmed the lack of evidence for adding metformin to clomiphene. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). Unlike women, whose fertility significantly declines after the age of 35, men’s fertility doesn’t decline until they are much older. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment.

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For instance, women with hyper or hypo-thyroidism sometimes have ovulation problems. In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1). Causes of Infertility Affecting Both Partners Some causes of infertility, such as psychological causes, may be relevant to both partners. After a woman ovulates, her body temperature rises by as much as 0. Adolescents with a varicocele and testicular atrophy or lack of growth should similarly consider repair. It is possible that this mechanism evolved to protect the mother’s health. In one study,  treatment with recombinant HBD1 in asthenozoospermic and leukocytospermic patients who were deficient in HBD1 resulted in improved bactericidal activity and sperm quality, which supports this protein’s role in fertility and its potential role in managing infertility.[28] Other causes Causes of testicular failure also include the following: Granulomatous disease – Leprosy and sarcoidosis may infiltrate the testicle Sickle cell disease – Sickling of cells within the testis leads to microinfarcts Excessive use of alcohol, cigarettes, caffeine, or marijuana Despite a thorough workup, nearly 25% of men have no discernible cause for their infertility. Source : Preserving your fertility - University of Kansas Hospital PPT Presentation Summary : Preserving your fertility. Counseling about options should be offered to couples who are not physically able to conceive (i.e., same-sex couples or persons lacking reproductive organs).