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These include: non-steroidal anti-inflammatory drugs (NSAIDs) – long-term use or a high dosage of NSAIDs, such as ibuprofen or aspirin, can make it more difficult to conceive chemotherapy – medicines used for chemotherapy can sometimes cause ovarian failure, which means your ovaries will no longer be able to function properly neuroleptic medicines – antipsychotic medicines often used to treat psychosis; they can sometimes cause missed periods or infertility spironolactone – a type of medicine used to treat fluid retention (oedema); fertility should recover around 2 months after you stop taking spironolactone Illegal drugs, such as marijuana and cocaine, can seriously affect fertility and make ovulation more difficult. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. Serum gonadotrophins (follicle-stimulating hormone and luteinising hormone) on Day2-3 especially in irregular periods. (N. Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of aspirin or ibuprofen may make it harder to conceive. Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary. (PDF, 438 KB) The New England Journal of Medicine, 2008.

More than 60% of sperm should be normal, and less than 2-3% should be immature. The main causes of tubal infertility are pelvic infections caused by bacteria such as chlamydia, previous abdominal disease or surgery and ectopic pregnancy. • Endometriosis is characterised by excessive growth of the lining of the uterus. Screening tests include increased plasma 17-hydroxylase and urine 17-ketosteroids. Ovarian Transplantation in a Series of Monozygotic Twins Discordant for Ovarian Failure. (PDF, 188 KB) The New England Journal of Medicine, 2007. Patients have with small- to normal-sized testes and azoospermia, but normal secondary sex characteristics.

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For in-vitro fertilization, a 100,000 of sperm are necessary and, for the intracytoplasmatic sperm injection, only a few sperms are required. This sterile needle is attached to sterile suction tubing and a collecting vial. Endometriosis causes infertility by producing inflammation and scarring, which can result in not only pain but also potentially detrimental effects on egg, sperm or embryo. Malformation of the eggs themselves may complicate conception.

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Causes of Female Infertility (Continued) Other causes of female infertility include: Local factors in the uterus and cervix, including uterine septum, uterine fibroids and endometriosis. Distribution of Spermatogenesis in the Testicles of Azoospermic Men: The Presence of Spermatids in the Testes of Men with Germinal Failure. (PDF, 295 KB) Human Reproduction, 1997.

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Endometriosis (especially if chronic), uterine fibroids (myomas), or an abnormally-shaped uterus might interfere with conception as well.  Age  As women grow older, it usually becomes more challenging for them to conceive. Following his lecture on laparoscopic appendectomy, the president of the German Surgical Society wrote to the Board of Directors of the German Gynecological Society suggesting suspension of Semm from medical practice. The use of Epididymal and Testicular Sperm for ICSI. (PDF, 1 MB) From IX World Congress on In Vitro Fertilization and Alternated Assisted Reproduction, 1995. If too many embryos develop, one or more can be removed. 8 If a woman has irregular cycles, the testing should be conducted later in the cycle, starting seven days before presumed onset of menses, and repeated weekly until menses. If this is unsuccessful, the dosage may be increased to 100 mg daily. If you suspect you are infertile, see your doctor. Get Permissions Email Alerts Don't miss a single issue. It is increasingly recognized that egg quality is of critical importance and women of advanced maternal age have eggs of reduced capacity for normal and successful fertilization.