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The Disappearing Y Chromosome – “I Told You So!” (PDF, 266 KB) Human Reproduction, 1997. Normal uterine implantation can therefore not occur. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. A spermiogram control study is performed after 3 cycles of therapy. If a woman has cycles at intervals of greater than 35 days, it may indicate that she is not ovulating an egg predictably, or even at all.

Assisted conception The following methods are currently available for assisted conception. This process bypasses the normal fertilization process, which may be compromised due to poor sperm function. Clean, Intermittent Self-catheterization in the Treatment of Urinary Tract Disease. (PDF, 2 MB) The Journal of Urology, 1972.

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Intracytoplasmic Sperm Injection and Infertility. (PDF, 53 KB) Nature Genetics, 2001. The uterine cavity is distended with a gas or liquid, and the hysteroscope is introduced into the uterine cavity which can then be carefully inspected. Testicular Sperm Extraction (TESE) and Intracytoplasmic Sperm Injection (ICSI) for Non-obstructive Azoospermia.(PDF, 1 MB) 10th World Congress on In Vitro Fertilization and Assisted Reproduction, 1997. Reduced fecundability in women with prenatal exposure to cigarette smoking.

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B.: No role for basal body temperature charts) Basic Work-up for Infertility 14. Ovarian reserve -More important in >35 years old, suspected ovarian failure and to detect response to ovulation induction. If he has two X chromosomes and one Y chromosome, as in Klinefelter's syndrome, the testicles will develop abnormally and there will be low testosterone and a low sperm count or no sperm. ICSI with Epididymal and Testicular Sperm Retrieval. (PDF, 1 MB) Male Sterility and Motility Disorders: Etiological Factors and Treatment, 1998. Hysterosalpingogram (HSG) – This test is essential for evaluating fallopian tubal patency, uterine filling defects such as fibroids and polyps, and scarring of the uterine cavity (Asherman syndrome).

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Ovulation-inducing drugs and ovarian cancer risk: results from an extended follow-up of a large United States infertility cohort. 41 Treatment of Unexplained Infertility Jump to section + Couples who have no identified cause of infertility should be counseled on timing of intercourse for the most fertile period (i.e., the six days preceding ovulation). Varicocele: Surgically removing a varicose vein in the scrotum may help. Low testosterone (male hypogonadism) and other hormonal problems have a number of possible underlying causes. Down syndrome These patients have mild testicular dysfunction with varying degrees of reduction in germ cell number. Between 45 and 50 percent of cases are thought to stem from factors that affect the man. Also, polymorphisms in folate pathway genes could be one reason for fertility complications in some women with unexplained infertility.[62] However, a growing body of evidence suggests that epigenetic modifications in sperm may be partially responsible.[63][64] Diagnosis[edit] If both partners are young and healthy and have been trying to conceive for one year without success, a visit to a physician or women's health nurse practitioner (WHNP) could help to highlight potential medical problems earlier rather than later. Treatment of tubal obstruction generally requires referral for subspecialty care. Generally, evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse.