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The use of Epididymal and Testicular Spermatozoa for Intracytoplasmic Sperm Injection: The Genetic Implications for Male Infertility. (PDF, 8 MB) Human Reproduction, 1995. Castration of the affected testis may allow the other testis to regain its ability to produce sperm, but the prognosis is guarded. Bromocriptine is used in cases when anovulation is caused by an elevated level of the hormone prolactin.

Some problems stop an egg being released at all, while others prevent an egg being released during some cycles but not others. BMI (body mass index) may be a significant factor in fertility, as an increase in BMI in the male by as little as three units can be associated with infertility. Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Urologic Clinics of North America, 1981.

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Endometriosis (especially if chronic), uterine fibroids (myomas), or an abnormally-shaped uterus might interfere with conception as well.  Age  As women grow older, it usually becomes more challenging for them to conceive. Some respond by actively avoiding the issue altogether; middle-class men are the most likely to respond in this way.[21] In the United States some treatments for infertility, including diagnostic tests, surgery and therapy for depression, can qualify one for Family and Medical Leave Act leave. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body.

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Lack of ovulation Patients with anovulation who did not ovulate after several cycles of CC at different doses of treatment are deemed clomiphene resistant. This mucus mainly affects the lungs, but males may also have a missing or obstructed vas deferens. As the duration of treatment prolonged, psychological suffering is likely to increase [6]. Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis.

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Some women are infertile because their ovaries do not mature and release eggs. The majority of men with varicocele present no symptoms. 8–16 One retrospective case-control study of 650 men with infertility and 698 control participants questioned the role of environmental risk; no association could be determined after assessing for multiple factors including shift work, stress, and pesticides. The sperm is washed in a fluid and the best specimens are selected. Ovulation disorders can be due to: Premature ovarian failure: The ovaries stop working before the age of 40 years. Gonadotropin release is modulated by various other signals, such as estradiol (a potent inhibitor of both LH and FSH release), and inhibin from the Sertoli cell, which causes a selective decrease in FSH release. Microsurgery and Andrology. (PDF, 5 MB) Chapter from textbook, 1991.