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Problems with sexual intercourse These can include trouble keeping or maintaining an erection sufficient for sex (erectile dysfunction), premature ejaculation, painful intercourse, anatomical abnormalities such as having a urethral opening beneath the penis (hypospadias), or psychological or relationship problems that interfere with sex. Human-beta defensin abnormalities Epididymis human-beta defensin is a protein that has been shown to have an important role in sperm maturation, and defects in it have been associated with decreased egg-penetrating ability.[27] One specific subtype, human-beta defensin-1 (HBD1), which has a wide distribution in various epithelia throughout the body and plays a role in antimicrobial activities against viruses, bacteria, and fungi, has also been investigated.

As the amount of adipose tissue increases, there is more aromatase available to convert androgens, and serum estradiol levels increase. Article Sections Infertility is defined as the inability to achieve pregnancy after one year of regular, unprotected intercourse. To reach timely ovulations, ovulation triggers are combined with chorionic gonadotropin (beta-HCG).

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Risk factors for both men and women are the same and these include age, stress, being underweight or overweight, diet, smoking, alcohol and drugs. Testicular Neoplasm in Father and Son. (PDF, 561 KB) The Journal of Urology, 1972. At least one open tube is required for IUI, and any sperm abnormality cannot be severe, otherwise the sperm will not be able to swim to and fertilize the egg. Congenital disorders and chryptorchidism (undescended testicles). Undescended testicles During fetal development one or both testicles may fail to descend from the abdomen into the sac that normally contains the testicles. The Relationship of Abnormal Semen Values to Pregnancy Outcome. (PDF, 770 KB) Chapter 10 from textbook, 1992.

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In some cases, the reproductive urologist can improve semen function by recommending certain lifestyle changes, by hormonal treatments, or by surgery. Women are advised not to use the drug for more than one day. Leydig cell function is impaired, and most patients are infertile due to primary testicular failure.

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Varicocele A varicocele is a swelling of the veins that drain the testicle, which can impact sperm quality. 30–32 Other treatment options include antiestrogens and gonadotropin therapy, which showed a trend toward increased live birth rates in a Cochrane review. Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Reproductive Endocrinology and Infertility. Follicle-stimulating hormone (Gonal-F, Bravelle): This hormone is produced by the pituitary gland that controls estrogen production by the ovaries. Irregular periods The average woman’s cycle is 28 days long. Hofherr SE, Wiktor AE, Kipp BR, Dawson DB, Van Dyke DL. Another requirement for male fertility is a normal ductal system. Fertility treatments for men Treatment will depend on the underlying cause of the infertility. It stimulates the ovaries to mature egg follicles. 3) Tubal occlusion (blockage): As discussed previously, a history of sexually transmitted infections including chlamydia, gonorrhea, or pelvic inflammatory disease can predispose a woman to having blocked fallopian tubes.