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Anatomic causes of infertility include acquired and congenital problems. 3  Sometimes, a couple who’ve already had a child can have trouble conceiving again. There are some common risk factors that can increase the likelihood of a man experiencing some form of reversible or permanent infertility.

We welcomed a sweet baby girl into the world in June this year!Background Infertility is a common clinical problem. If they're damaged, it can seriously affect the quality of your semen.

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These may cause abortion, neonatal death, fetal resorption, and apparent infertility. Examples of such health issues include infections, endometriosis, and fibroids. Gonadotropins can trigger ovulation when Clomid or Serophene don't work.

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Endometrial polyps Endometrial polyps are growths found in the uterine cavity. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Hypospadias: The urethral opening is under the penis, instead of its tip. Idiopathic Hypercalciuria. (PDF, 1 MB) New England Journal of Medicine, 1971. KU School of Medicine Source : Are Twins An Adverse Outcome After Infertility Treatments?

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In a recent meta-analysis, letrozole was found to be as effective as other methods of ovulation induction. [169] The usual dose for letrozole ovulation induction is 2. Gerrits T, Shaw M (2010). "Biomedical infertility care in sub-Saharan Africa: a social science review of current practices, experiences and view points". Come and meet us to find out more about how we can help you. After stimulation, the physician surgically extracts one or more eggs from the ovary, and unites them with sperm in a laboratory setting, with the intent of producing one or more embryos. Unexplained infertility[edit] In the US, up to 20% of infertile couples have unexplained infertility.[61] In these cases abnormalities are likely to be present but not detected by current methods. Online support from organizations such as Resolve can be helpful. IVF and related techniques (ICSI, ZIFT, GIFT) are called assisted reproductive technology (ART) techniques. Outlook For couples who experience fertility problems and those who wish to have children at an older age, there are more options available than ever before. Klinefelter�s Syndrome: Is a genetic condition in which each cell in the human body has an additional X chromosome--men with Klinefelter�s Syndrome have one Y and two X chromosomes.  Physical symptoms include peanut-sized testicles and enlarged breasts.  A chromosome analysis is used to confirm this analysis.  If this condition is treated in its early stages (with the drug hCG), sperm production may commence and/or improve.  However, Klinefelter�s Syndrome eventually causes all active testicular structures to atrophy.  Once testicular failure has occurred, improving fertility is impossible. The predictive value of hysterosalpingography for tubal and peritoneal infertility factors. In-vitro fertilization (IVF): Sperm are placed with unfertilized eggs in a petri dish, where fertilization can take place. It is often prescribed for Crohn's disease or rheumatoid arthritis.