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They can also carry out some basic tests on both partners to see if there is an identifiable reason for not having achieved a pregnancy. Close Common Causes of Female Sterility The most common causes of female sterility include: Fallopian tube damage or blockage Ovulation disorders Polycystic ovary syndrome (PCOS) Endometriosis Early menopause Pelvic adhesions Benign uterine fibroids Close Help for Sterility Sexual problems such as impotence or premature ejaculation should be addressed. 8,46 Obesity impairs fertility and the response to fertility treatments, including in vitro fertilization; therefore, it is advisable to counsel patients who are obese to lose weight before conception or infertility treatments. Surgical Intervention Uterine anomalies can be corrected through operative hysteroscopy under general anesthesia or conscious sedation. [116] Ideally, the procedure should be performed during the early follicular phase and under laparoscopic surveillance to decrease the risk of uterine perforation. Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Journal of Andrology, 1980. They can often recommend a counselor and others who can offer appropriate support.

Unexplained infertility[edit] In the US, up to 20% of infertile couples have unexplained infertility.[61] In these cases abnormalities are likely to be present but not detected by current methods. The problem is getting the sperm where they need to go. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics. This can reveal signs of endometriosis, scarring, blockages, and some irregularities of the uterus and fallopian tubes.

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Production of the First Offspring from Oocytes Derived from Fresh and Cryopreserved Pre-antral Follicles of Adult Mice. (PDF, 2 MB) Reproductive BioMedicine Online, 2007. This hormone then binds to another area of the brain called the pituitary gland and leads to the release of FSH (follicle stimulating hormone), a hormone that directly binds to cells in the ovary, leading to egg growth and maturation. 38,39 Family physicians may choose to attempt ovulation induction in anovulatory women (WHO group II) with clomiphene. Any abnormality in the tubes can affect or impede conception: hydrosalpinx, tubal occlusion or salpingitis. Chlamydia test: Chlamydia can affect fertility, but antibiotics can treat it. Your doctor will carry out a series of tests to diagnose what’s causing your fertility difficulties.  There are many reasons why you may have problems conceiving, including:  Your sperm does not have the concentration, motility or shape required to conceive Existing medical conditions that affect your fertility, such as issues with sperm production or duct obstructions  Your sperm may not be strong or healthy enough to fertilise your partner’s egg  As your partner gets older, her fertility quickly declines3 Depending on the cause, your doctor will recommend a treatment path for you.

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Couples who do not conceive after treatment for six cycles with documented ovulation should also consider referral to an infertility specialist. Several days later, embryos -- or fertilized eggs -- get put back into your uterus with a device called an intrauterine insemination catheter.

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The volume provides clear guidelines and a logical sequence of steps which will quickly lead the clinician or physician to an accurate diagnosis of the underlying cause of infertility. Methodology This paper, as a comprehensive review, deploys a new strategy to translate the research findings and evidence-base recommendations into a simplified focused guide to be applied on routine daily practice. Are Sequence Family Variants Useful for Identifying Deletions in the Human Y Chromosome? (PDF, 377 KB) The American Journal of Human Genetics, 2004. They can also carry out some basic tests on both partners to see if there is an identifiable reason for not having achieved a pregnancy. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. World Health Organization[edit] The World Health Organization defines infertility as follows:[10] United States[edit] One definition of infertility that is frequently used in the United States by reproductive endocrinologists, doctors who specialize in infertility, to consider a couple eligible for treatment is: a woman under 35 has not conceived after 12 months of contraceptive-free intercourse. Povey AC, Clyma JA, McNamee R, et al.; Participating Centres of Chaps-UK. One type of ovulation problem, polycystic ovarian syndrome, is effectively treated with medications. Treatment of Female Infertility: Ovulation Induction Agents The main agents used for the induction of ovulation include: Clomiphene citrate is an orally active, nonsteroidal agent structurally similar to estrogen. Ovulatory menstrual periods tend to be regular and predictable in terms of cycle length, duration and heaviness of bleeding, and other symptoms. Patients who do not ovulate because of a fault in the pituitary gland may receive this drug as an injection.