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50% are female causes with 25% being due to anovulation and 25% tubal problems/other.[74] In Sweden, approximately 10% of couples wanting children are infertile.[75] In approximately one third of these cases the man is the factor, in one third the woman is the factor, and in the remaining third the infertility is a product of factors on both parts. Assisted conception The following methods are currently available for assisted conception. Simultaneous Treatment of the Wife in Infertile Couples with Oligospermia. (PDF, 4 MB) Fertility and Sterility, 1983. Ovulation problems can be a result of:  polycystic ovary syndrome (PCOS) thyroid problems – both an overactive thyroid gland and an underactive thyroid gland can prevent ovulation premature ovarian failure – where a woman's ovaries stop working before the age of 40 Scarring from surgery Pelvic surgery can damage and scar the fallopian tubes, which link the ovaries to the womb. They can be blocked due to numerous causes, including infections,  trauma or abnormal development, such as with cystic fibrosis or similar inherited conditions. In order to maximize the patient’s chances for successful fertilization, physicians typically use ovarian stimulation medications rather than using the single egg normally developed each cycle.

Your doctor will analyze your semen analysis carefully and help you decide if ICSI is an appropriate treatment for you. Causes of infertility and sterility in men The male factor is difficult to evaluate because sperm analyses do not always indicate if there is a problem or not. With this treatment, the patient experience spermatogenesis, and therefore, it has the chance to have offspring if he wants to.

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Once a diagnosis has been made, you and your partner can consider the various treatment options. Your doctor may suggest that you take gonadotropin if you have unexplained infertility or when other kinds of treatment haven't helped you get pregnant. Laparotomy with histopathology is usually indicated, because medical attempts at inducing ovulation (human chorionic gonadotropin, FSH, GnRH) are usually unrewarding. Semen and sperm Sometimes the sperm cannot travel effectively to meet the egg. Approximately 10% of cases are unexplained, where no definitive cause can be identified.

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Men who are underweight tend to have lower sperm concentrations than those who are at a normal BMI. Coutifaris C, Myers ER, Guzick DS, et al.; NICHD National Cooperative Reproductive Medicine Network.

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549 KB Effect of Age on Male Fertility. (PDF, 5 MB) Chapter from textbook, Seminars in Reproductive Endocrinology, 1991. The new generations of available gonadotropins are produced by genetically engineered mammalian cells (ie, Chinese hamster ovary cells), in which the gene coding for the alpha and beta FSH subunits has been inserted (follitropin alfa [eg, Gonal F] and follitropin beta [eg, Follistim AQ]). [185] Recombinant LH may beaddedtorecombinantFSHprotocolsasanalternative,particularlyuseful in patients with hypothalamic amenorrhea. At least one open tube is required for IUI, and the sperm abnormality cannot be severe otherwise the sperm will not be able to swim to and fertilize the egg. Trauma Testicular trauma is the second most common acquired cause of infertility. Anatomic causes of infertility include acquired and congenital problems. Although many of these can be treated through surgery or hormonal substitutions, some may be indefinite.[59] Infertility associated with viable, but immotile sperm may be caused by primary ciliary dyskinesia. Treatment Treatment will depend on many factors, including the age of the person who wishes to conceive, how long the infertility has lasted, personal preferences, and their general state of health. You have never had a period, or periods suddenly stop. Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Radiopaque dye is instilled into the uterine cavity through the cervix and x-rays are taken. No Differences in Outcome after Intracytoplasmic Sperm Injection with Fresh or with Frozen-thawed Epididymal Spermatozoa. (PDF, 66 KB) Human Reproduction, 1999. The authors of the new global standards said the revised definition gave every individual “the right to reproduce.” Until now, the WHO’s definition of infertility—which it classed as a disability—has been the failure to achieve pregnancy after 12 months or more of regular unprotected sex. IVF/ICSI is a process by which the oocyte is fertilized by a sperm outside the body: in vitro, and then a gamete retransferred intrauterine. New Treatment for Infertility Due to Congenital Absence of Vas Deferens. (PDF, 1 MB) The Lancet, 1987.