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WHO categorizes ovulatory disorders into three groups: group I is caused by hypothalamic pituitary failure (10%), group II results from dysfunction of hypothalamic-pituitary-ovarian axis (85%), and group III is caused by ovarian failure (5%). The ideal response is one in which only 2-3 follicles develop. For example, endometriosis can cause infertility with the growth of endometrial tissue in the Fallopian tubes or around the ovaries. Aromatase inhibitors Aromatase inhibitors (letrozole, anastrozole) inhibit the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. Sperm are then collected, washed, and added to the eggs in the dish.

Overweight or obesity: This may reduce the chance of conceiving. Additionally, the sperm may be unable to cross the cervical mucus or may have ultrastructural abnormalities.

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Hyperprolactinemia: If prolactin levels are high, and the woman is not pregnant or breastfeeding, it may affect ovulation and fertility. 2 This encompasses couples with infertility and impaired ability to get pregnant, but it does not capture those who are not married, so actual numbers may be underestimated. In a third of cases, the reason lies only with the man; in another third, it is because of the woman; and in the rest of the cases, it is a combination of both, or the cause is unknown. Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary. (PDF, 438 KB) The New England Journal of Medicine, 2008.

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Legal, cultural and religious inquiries have limited the available choices in some countries, such as the use of donor sperms or oocytes. Legal, cultural and religious inquiries have limited the available choices in some countries, such as the use of donor sperms or oocytes. Patients are often short, with small firm testis and gynecomastia, but they have a normal-sized penis. Anabolic steroids: Popular with bodybuilders and athletes, long-term use can seriously reduce sperm count and mobility. Other testing may be needed based on circumstances, including testicular biopsy, genetic testing, and imaging (Table 36–8,10,19,20).

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Tubal catheterisation or cannulation: - With proximal tubal obstruction, selective salpingography plus tubal catheterisation, or hysteroscopic tubal cannulation, may be treatment options. Although many of these can be treated through surgery or hormonal substitutions, some may be indefinite.[59] Infertility associated with viable, but immotile sperm may be caused by primary ciliary dyskinesia. If this is unsuccessful, the dosage may be increased to 100 mg daily. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. However, it could be the future for the treatment of multiple diseases, including infertility. With this condition, boys are born with a different chromosomal make-up, generating an absence of spermatozoa production or minimum generation of sperm that ceases at an early age. Symptoms of hormonal imbalance: Sudden weight gain, hair loss, constant fatigue, edema, headaches, nipple discharge, facial hair, or severe acne are all signs of possible hormonal disorders. Many uterine and tubal abnormalities detected by the HSG can be surgically corrected.