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Paternal age > or = 40 years: an important risk factor for infertility. The normal working of the male reproductive system involves first the production of sufficient numbers of functional sperm cells and then the delivery of these sperm to the ejaculate. They are very common (approximately 40% of women have them them). During ejaculation, the ejaculate is propelled forward by the rhythmic contractions of the smooth muscle that surrounds the ducts and by the bulbourethral muscles and other pelvic muscles. Radiation therapy: This can impair sperm production. Causes[edit] Hormonal imbalance[edit] This is the most common cause of anovulation and is thought to account for about 70% of all cases.

Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994. Microsurgical Epididymal Sperm Aspiration and Assisted Reproductive Techniques. (PDF, 4 MB) Frontiers in Human Reproduction, 1991. Search dates: January 6, 2014; January 28, 2014; February 5, 2014; and November 18, 2014.

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Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. Tubal occlusion is a cause of infertility because an ovulated egg is unable to be fertilized by sperm or to reach the endometrial cavity.

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Understanding the normal reproductive process is essential in knowing when to seek help. Urinary monitoring of the LH surge (eg, with an LH Predictor Kit) can be a substitute for BBT.

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Careful monitoring during treatment and pregnancy can help reduce the risk of complications. The Relationship of Abnormal Semen Parameters to Male Fertility. (PDF, 4 MB) Human Reproduction, 1989. Atrophy is observed within 1-6 months, and the degree of atrophy does not correlate with the severity of orchitis or infertility. Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of aspirin or ibuprofen may make it harder to conceive. Prevalence of Premature Ovarian Failure in Monozygotic and Dizygotic Twins. (PDF, 90 KB) Human Reproduction, 2007. Sperm Retrieval for Azoospermia and Intracytoplasmic Sperm Injection Success Rates – A Personal Overview.(PDF, 1 MB) Human Fertility, 2010. Zygote Intrafallopian Transfer (ZIFT) Zygote Intrafallopian Transfer (ZIFT) is another variation of IVF. Sperm Granuloma and Reversibility of Vasectomy. (PDF, 11 MB) Lancet, 1977. Long-term Economic Benefits Attributed to IVF-conceived Children: A Lifetime Tax Calculation. (PDF, 225 KB) The American Journal of Managed Care, 2008.