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One of the best known is the HFEA – The UK's regulator for fertility treatment and embryo research. Pregnancies after Testicular Sperm Extraction and Intracytoplasmic Sperm Injection in Non-obstructive Azoospermia. (PDF, 3 MB) Human Reproduction, 1995. A cumulative pregnancy rate of 80% is achieved during the first 6 cycles of therapeutic insemination.

Several studies have reported different causes of infertility [7-9]. Operative hysteroscopy associated with tubal cannulation is helpful to treat cornual obstruction. Epidemiology of infertility For healthy young couples, the probability of getting pregnancy per a reproductive cycle is about 20% to 25%. If he has two X chromosomes and one Y chromosome, as in Klinefelter's syndrome, the testicles will develop abnormally and there will be low testosterone and a low sperm count or no sperm. 0.[44] Environmental factors Toxins such as glues, volatile organic solvents or silicones, physical agents, chemical dusts, and pesticides.[45][46] Tobacco smokers are 60% more likely to be infertile than non-smokers.[47] German scientists have reported that a virus called adeno-associated virus might have a role in male infertility,[48] though it is otherwise not harmful.[49] Other diseases such as chlamydia, and gonorrhea can also cause infertility, due to internal scarring (fallopian tube obstruction).[50][51][52] Alimentary habits[53] Obesity: The obesity epidemic has recently become is a serious issue, particularly in industrialized nations. The Avon Longitudinal Study of Pregnancy and Childhood Study Team.

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Inhibin B levels have been reported to decrease with increasing weight, which results in decreased Sertoli cells and sperm production. Basic Work-up for Infertility It is very important to remember that infertility can occur as a result of one or more male or female factors. Clomiphene citrate and/or Metformin. - folliculometry via TVUSS should be done to avoid multiple pregnancies and risk of OHSS. - Not for more than 6 months. This semiautomated technique is thought to potentially standardize the evaluation of semen. Surgical Management of Male Infertility. (PDF, 2 MB) Chapter 12 from textbook, Male Infertility, 1992.

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Other causes of ovulation disorders include ovarian insufficiency and hypothalamic amenorrhea. Laurence-Moon-Biedl syndrome Patients with this syndrome have retinitis pigmentosa and polydactyly. Before performing a tubocornual anastomosis, the patient should have a diagnostic laparoscopy associated with tubal cannulation by hysteroscopy. [139, 140, 141] If one tube remains open, anastomosis is not needed because pregnancy can be achieved in 50% of cases.

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Other causes of infertility affecting both partners include immunological incompatibility between sperm and the cervical mucus, which may in some instances cause sperm agglutination. In patients with nonobstructive azoospermia, retrograde ejaculation can be the etiologic factor. [107] The treatment consists of recovering sperm from a urine sample collected immediately after ejaculation. These and many other questions will help your physician design a specific evaluation and potential treatment for you. In another 30% of all cases, the cause is in the male partner. Testosterone therapy may allow patients to achieve normal height but does not improve spermatogenesis.