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Ovulation disorders About one quarter of infertility cases are due to ovulation disorders. As there is surplus medical information everyday that can not be cached by healthcare providers, clinical guidelines created to endorse up-to-date evidence-based practice to improve patients' outcome [6]. Female factor Dysfunction of the female reproductive organs is also apparent in around 40% of infertile couples. A needle biopsy of the testicle can show whether a man is making healthy sperm. A doctor may diagnose infertility if a woman has not become pregnant after 1 year of trying. Therefore, it is particularly important to evaluate both partners when investigating infertility.

6 million (6%) married women aged 15–44 years in the United States reported difficulty getting pregnant (3). Endometrial polyps Endometrial polyps are growths found in the uterine cavity. Recombination Between Palindromes P5 and P1 on the HUman Y Chromosome Causes Massive Deletions and Spermatogenic Failure. (PDF, 786 KB) The American Journal of Human Genetics, 2002. 42 However, none of these methods has been proven to increase pregnancy rates when used to predict timing of intercourse. If conception does not occur after many months or years of trying, it can lead to stress and possibly depression. Congenital Absence of the Vas Deferens: The Fertilizing Capacity of Human Epididymal Sperm. (PDF, 3 MB) New England Journal of Medicine, 1990.

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Testicular histology typically reveals a decreased number of Leydig cells and decreased spermatogenesis. Nonchromosomal testicular failure Testicular failure that is nonchromosomal in origin may be idiopathic or acquired by gonadotoxic drugs, radiation, orchitis, trauma, or torsion.

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Fresh Ovarian Tissue and Whole Ovary Transplantation. (PDF, 373 KB) Seminars in Reproductive Medicine, 2009. For example, high cortisol levels are seen in patients with Cushing syndrome, which causes negative feedback on the pituitary to decrease LH release.

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Aetiology of Congenital Absence of Vas Deferens: Genetic Study of Three Generations. (PDF, 4 MB) Human Reproduction, 1993. This is called luteinised unruptured follicle syndrome (LUFS). It varies with the age (the optimal female age is between 23 and 39 years) and with body weight (the ideal body mass index is between 19 and 30). 8 Counseling on lifestyle modifications is reasonable because exposures to tobacco and alcohol are associated with lower rates of fertility. 8,33,35,36 Lastly, in vitro fertilization, with or without intracytoplasmic sperm injection, is the mainstay of assisted reproductive technology for male factor infertility. Tubal obstruction due to elective sterilization is better repaired with microsurgery, although the modern tendency is to perform the anastomosis using operative laparoscopy. [33, 143, 144] In either event, knowing in advance what type of tubal ligation technique was used is important. Because the sperm have a short life span outside the human body, the semen specimen must be evaluated within a short time frame. For example, endometriosis can cause infertility with the growth of endometrial tissue in the Fallopian tubes or around the ovaries. Epidemiological definition of infertility (for monitoring and surveillance) Women of reproductive age (15–49 years) at risk of becoming pregnant (not pregnant, sexually active, not using contraception and not lactating) who report trying unsuccessfully for a pregnancy for two years or more. (Reproductive Health Indicators) Infertility as a disability Disability: Infertility generates disability (an impairment of function), and thus access to health care falls under the Convention on the Rights of Persons with Disability. The Most Common Causes of Male Sterility There are several causes of male sterility, including: Abnormal sperm production Impaired delivery of sperm Testosterone deficiency Genetic defects Undescended testes Also, erectile dysfunction or low libido can make the process of procreation that much more difficult. Endometriosis causes infertility by producing inflammation and scarring, which can result in not only pain but also potentially detrimental effects on egg, sperm or embryo. 38,39 Family physicians may choose to attempt ovulation induction in anovulatory women (WHO group II) with clomiphene.