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In humans, infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner.[2] There are many causes of infertility, including some that medical intervention can treat.[3] Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997. Antibodies that are bound to sperm decrease the sperm’s ability to penetrate the cervical mucus and bind to the zona pellucida. Infertility in women was ranked the 5th highest serious global disability5&6 (among populations under the age of 60). Your doctor will determine if you are at risk of having endometriosis based on a careful history, physical exam, and ultrasound. Clinical Characterization of 42 Oligospermic or Azoospermic Men with Microdeletion of the AZFc Region of the Y Chromosome, and of 18 Children Conceived via ICSI. (PDF, 606 KB) Human Reproduction, 2002.

For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. Low sperm mobility (motility): The sperm cannot "swim" as well as they should to reach the egg. It is increasingly recognized that egg quality is of critical importance and women of advanced maternal age have eggs of reduced capacity for normal and successful fertilization.

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You made this process easier by being supportive and positive. IUI is more commonly done when the man has a low sperm count, decreased sperm motility, or when infertility does not have an identifiable cause. Laparoscopic cholecystectomy is the most common laparoscopic procedure performed.

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Intracytoplasmic Sperm Injection. (PDF, 4 MB) Chapter 47 from textbook Current Therapy in Equine Reproduction, 2006. Causes of Female Infertility The following causes may lead to infertility in women: Pelvic inflammatory disease, which can lead to blocked or damaged fallopian tubes. Blockage of the ejaculatory duct: Sperm can be extracted directly from the testicles and injected into an egg in the laboratory.

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WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple. Evaluation of the uterus and fallopian tubes can be performed by hysterosalpingography in women with no risk of obstruction. Over the past three decades, huge advancements in fertility science have helped millions of couples to overcome their difficulties and have children of their own. Round Spermatid Injection. (PDF, 422 KB) Fertility and Sterility, 2000.