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In addition to the alteration of menstrual periods and infertility, chronic anovulation can cause or exacerbate other long term problems, such as hyperandrogenism or osteopenia. The acrosome, a derivative of the Golgi process, surrounds the nucleus anteriorly and contains enzymes necessary to penetrate the ovum. Overweight or obesity: This may reduce the chance of conceiving.

A sperm count of under 15 million is considered low. Any abnormality in the tubes can affect or impede conception: hydrosalpinx, tubal occlusion or salpingitis.

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Causes of Sterility in Women In women, the classification of possible causes is much more complex. Some methods may be used in concert with other methods. Gonadotropin-releasing hormone (GnRH) from the hypothalamus stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary. One of the requirements for this procedure is that a woman should have at least 1 undamaged fallopian tube. Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[56] or her age as female fertility declines after the age of 30.[57] Sometimes it can be a combination of factors, and sometimes a clear cause is never established. Normal Fertilization of Human Oocytes after Testicular Sperm Extraction and Intracytoplasmic Sperm Injection.(PDF, 2 MB) Fertility and Sterility, 1994.

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Eating disorders: If an eating disorder leads to serious weight loss, fertility problems may arise. Blood, urine, and imaging tests can be done to discover why you are having trouble getting pregnant. Sperm density Normal sperm density is greater than 20 million sperm/mL. This procedure is performed in the doctor’s office without anesthesia.

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Ultrasound: This may reveal issues such as ejaculatory duct obstruction or retrograde ejaculation. A penile exam should detect atrophy, tumors, epididymal cysts, cryptorchidism (undescended testicles), vas thickening or absence of the vas deferens, hydrocele (fluid accumulation in the testis or along the spermatic cord) or varicocele. Patients have eunuchoidal body habitus, large testis, and a low ejaculatory volume. When Predictions Don’t Predict. (PDF, 549 KB) The Australian and New Zealand Journal of Obstetrics and Gynaecology, 1991. Sperm are then collected, washed, and added to the eggs in the dish. The opening improves the ability of the embryo to implant into the uterine lining. Twelve months is the lower reference limit for Time to Pregnancy (TTP) by the World Health Organization.[7] a woman over 35 has not conceived after six months of contraceptive-free sexual intercourse. About 10% of reproductive age women are affected by endometriosis. Diverse Spermatogenic Defects in Humans Caused by Y Chromosome Deletions Encompassing a Novel RNA-binding Protein Gene. (PDF, 2 MB) Human Reproduction, 1996. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). In my case, the inability to conceive was the result of a condition called stage 4 endometriosis.