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Causes of Infertility and Sterility

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8 However, if your doctor diagnoses you with infertility, then it’s likely that you’ll need some additional help to conceive.  This may be as simple as timing when you have sex, or you may need more advanced fertility treatment.   Discovering that you’re infertile can be overwhelming, but the right support can help you to conceive successfully. There is no reliable treatment, although microsurgery may be attempted. Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. The relation between daily activities and scrotal temperature. Financing fertility treatment can also be costly, but there are programs that can help with this.Infertility is the inability of a person, animal or plant to reproduce by natural means.

Other conditions Various other lesions and diseases, such as CNS tumors, temporal lobe seizures, and many drugs (eg, dopamine antagonists) may interrupt the hypothalamic-pituitary axis at the hypothalamus. Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of aspirin or ibuprofen may make it harder to conceive. The epididymis is a coil-like structure in the testicles which helps store and transport sperm.

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Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. Women with anovulation may be treated in the primary care setting with clomiphene to induce ovulation. Gonadotropin releasing hormone analogs (GnRH-a) are synthetic peptides whose structure is similar to the natural GnRH. A blood test done on days 21 or 22 of a normal 28-day menstrual cycle can be used to test whether ovulation has occurred by measuring the progesterone level. If your cycles are infrequent or irregular, your doctor will examine you and perform the appropriate testing to discover which problem you may have and present the appropriate treatment options. Low testosterone (male hypogonadism) and other hormonal problems have a number of possible underlying causes.

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Unlike women, whose fertility significantly declines after the age of 35, men’s fertility doesn’t decline until they are much older. Fertilization takes place outside the body, and the fertilized egg is reinserted into the woman's reproductive tract, in a procedure called embryo transfer.

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Algorithm for infertility evaluation. (ART = assisted reproductive technology.) Lifestyle Factors Jump to section + All couples should be counseled to abstain from tobacco use, limit alcohol consumption, and aim for a body mass index less than 30 kg per m2 to improve their chances of natural conception or using assisted reproductive technology. Especially in men, psychological explanations should be considered as they are frequently the cause of sexual dysfunctions. The chromosomal pattern of the resultant embryos can be assessed with preimplantation genetic diagnosis. Luciano AA, Peluso J, Koch EI, Maier D, Kuslis S, Davison E. Reproductive Biology. (PDF, 147 KB) The Scientist, 1996. Diverse Spermatogenic Defects in Humans Caused by Y Chromosome Deletions Encompassing a Novel RNA-binding Protein Gene. (PDF, 7 MB) Nature Genetics, 1995. Pregnancy after Vasovasostomy for Vasectomy Reversal: A Study of Factors Followed for 10 Years. (PDF, 3 MB)Human Reproduction, 1989. Ovarian dysfunction, when a woman’s ovaries are not producing eggs, or egg production has diminished due to hormonal imbalance, age or other factors. Apparent Fertility of Human Spermatozoa from the Caput Epididymidis. (PDF, 4 MB) Journal of Andrology, 1989. Exercise: Both too much and too little exercise can lead to fertility problems. 8,33,35,36 Lastly, in vitro fertilization, with or without intracytoplasmic sperm injection, is the mainstay of assisted reproductive technology for male factor infertility.


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