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Microsurgery in Pediatric Urology. (PDF, 13 MB) The National Foundation, 1977. The Fate of Non-absorbable Intraureteral Suture. (PDF, 233 KB) The Journal of Urology, 1973. Article Sections Infertility is defined as the inability to achieve pregnancy after one year of regular, unprotected intercourse. Intra-uterine insemination for unexplained subfertility. These abnormalities can also cause irregular bleeding between menstrual cycles. The most commonly prescribed pill to stimulate ovulation (generally of one mature egg) is clomiphene citrate.

A variety of disorders ranging from hormonal disturbances to physical problems, to psychological problems can cause male infertility.  Although many treatment options are now available, in many cases treatment will not work.  In many instances, male infertility is caused by testicular damage resulting in an inability of the testicle to produce sperm.  Once damaged, the testicle will not usually regain its sperm-making capabilities; this aspect of male infertility is analogous to menopause (though not natural like menopause) for women and cannot usually be treated.  Despite medicine�s limited ability to treat male infertility, many successful treatment options are available for its many causes.  Besides testicular damage, the main causes of male infertility are low sperm production and poor sperm quality.   The Causes of Male Infertility Male infertility has many causes--from hormonal imbalances, to physical problems, to psychological and/or behavioral problems.  Moreover, fertility reflects a man�s �overall� health.  Men who live a healthy lifestyle are more likely to produce healthy sperm.  The following list highlights some lifestyle choices that negatively impact male fertility--it is not all-inclusive: · Smoking--significantly decreases both sperm count and sperm cell motility. · Prolonged use of marijuana and other recreational drugs. · Chronic alcohol abuse. · Anabolic steroid use--causes testicular shrinkage and infertility. · Overly intense exercise--produces high levels of adrenal steroid hormones which cause a    testosterone deficiency resulting in infertility. · Inadequate vitamin C and Zinc in the diet. · Tight underwear--increases scrotal temperature which results in decreased sperm production. · Exposure to environmental hazards and toxins such as pesticides, lead, paint, radiation, radioactive   substances, mercury,  benzene, boron, and heavy metals · Malnutrition and anemia. · Excessive stress! Nevertheless, scientists have found these stem cells, which may generate new oocites in postnatal conditions. 8 Counseling on lifestyle modifications is reasonable because exposures to tobacco and alcohol are associated with lower rates of fertility.

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Patients who do not achieve ovulation after three to six cycles should be referred to an infertility specialist for further treatment. Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens. (PDF, 5 MB) New England Journal of Medicine, 1995.

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It is better for a couple to see the doctor together. While BBT is an inexpensive way to monitor ovulation, it is often impractical.

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Gonadotropin release is modulated by various other signals, such as estradiol (a potent inhibitor of both LH and FSH release), and inhibin from the Sertoli cell, which causes a selective decrease in FSH release. In cases of poor sperm quality, intrauterine insemination can be performed. Noonan syndrome (46, XY) Patients with Noonan syndrome, also known as male Turner syndrome, have physical characteristics similar to that of women with Turner syndrome (45, X). Also possible is increased body mass and facial hair, which is relatively easy to treat, and is often associated with PCOS, or polycystic ovary syndrome. Furthermore, if there is a background of gynaecological or andrological issues in the couple, a study should be carried out as soon as possible. Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes. (PDF, 1 MB) Cell, 2009. Blocked tubes Sperm travel in tubes from the man’s testes to the penis. Moderate alcohol consumption has not been shown to lower fertility in most men, but it may affect those who already have a low sperm count. Peritubaric adhesions can be caused by endometriosis. This is obviously extremely distressing for the couples involved. When Predictions Don’t Predict. (PDF, 549 KB) The Australian and New Zealand Journal of Obstetrics and Gynaecology, 1991. This diagnosis is therefore shared by 15% of couples attempting to conceive. Causes of Sterility in Women In women, the classification of possible causes is much more complex. These questions will be regarding your medical, surgical, gynecological, and obstetric history, as well as some lifestyle questions.