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Advances in assisted reproductive technologies, such as IVF, can offer hope to many couples where treatment is available, although barriers exist in terms of medical coverage and affordability. Eating disorders such as anorexia nervosa are also associated with extremely low BMI. One of the common causes of infertility is infrequent intercourse.

The average pregnancy rate achieved after a natural-cycle intrauterine insemination is 8%. For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. The main side effects are hot flushes, gastrointestinal events (nausea and vomiting), headache, back pain, and leg cramps.

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Most couples skip the invasive laparoscopic surgery and do treatments with intrauterine inseminations and then IVF if inseminations are not successful. Intra-uterine insemination for male subfertility. In 30% of all cases, the cause is in both partners: combined sterility. In some cases, the cause of infertility or subfertility could not be suspected from the history taking and clinical examination.

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The incidence of congenital malformation in IVF babies ranges between 2% and 3% worldwide and is similar to that in babies conceived naturally [45]. Algorithm for infertility evaluation. (ART = assisted reproductive technology.) Infertility Evaluation Figure 1. World Health Organization reference values for human semen characteristics.

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Laparoscopy is an operation performed in the abdomen or pelvis through small incisions, generally no more than a centimeter, with the assistance of a laparoscope attached to a camera which projects to a screen. Anabolic steroids: Popular with bodybuilders and athletes, long-term use can seriously reduce sperm count and mobility. 8,33,35,36 Lastly, in vitro fertilization, with or without intracytoplasmic sperm injection, is the mainstay of assisted reproductive technology for male factor infertility. Rarely, a blood clot may develop in an artery or vein, liver or kidney problems can arise, and respiratory distress may develop. M. genitalium infection is associated with increased risk of infertility.[25][26] Genetic[edit] A Robertsonian translocation in either partner may cause recurrent spontaneous abortions or complete infertility.[citation needed] Mutations to NR5A1 gene encoding Steroidogenic Factor-1 (SF-1) have been found in a small subset of men with non-obstructive male factor infertility where the cause is unknown.