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10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. However, some have suggested that patients should avoid conception for 6 months to 2 years after completion of radiation therapy because of the possibility of chromosomal aberrations in their sperm caused by the mutagenic properties of radiation therapy.

There are many disorders that may impact the ability for a woman to ovulate normally. Disadvantages of IVF include failure to conceive, OHSS and expensiveness.

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Age: Male fertility starts to fall after 40 years. CC is a nonsteroidal estrogen capable of interacting with estrogen receptor–binding proteins in a manner similar to estrogen but in a more prolonged way. [159, 160] Therefore, CC behaves similar to an antiestrogen.

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This test is based on the fact that the ovaries produce progesterone in the second half of the menstrual cycle after a woman has ovulated. Treatment of tubal obstruction generally requires referral for subspecialty care.

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Guidance from the National Institute for Health and Care Excellence (NICE) says women under the age of 42 should be offered three full cycles of IVF, with access for same-sex couples if surrogacy or privately funded fertility treatment fails. Microsurgical Epididymal Sperm Aspiration and Assisted Reproductive Techniques. (PDF, 4 MB) Frontiers in Human Reproduction, 1991. However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. Prolactinomas or the intakes of dopamine antagonists (typical antipsychotics for example) cause hyperprolactinemia. In 1978, the first baby was born as a result of IVF. Some physical effects may also result from treatment.